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High purity and accurate concentration.
High Purity
Accurate
No Harmful Additives
Human Menopausal Gonadotropin
- This compound requires bacteriostatic water for reconstitution.
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Product Information
A urinary-derived glycoprotein hormone preparation containing both FSH and LH in approximately 1:1 ratio, FDA-approved for female infertility (ovulation induction, ART) and male hypogonadotropic hypogonadism. First used clinically in 1961 by Bruno Lunenfeld, HMG enabled the birth of the first American IVF baby in 1981 and remains a cornerstone of fertility medicine with over 60 years of clinical experience. Highly purified preparations (HP-hMG) demonstrate comparable or slightly superior live birth rates compared to recombinant FSH in IVF.
Product Overview
Mechanism of Action
HCG activates LH receptors in the testes, stimulating Leydig cells to produce testosterone. In women, it can trigger final follicular maturation and ovulation when used in appropriate fertility protocols.
Its effects depend on the individual’s underlying hormonal function and clinical indication.
Mechanism of Action
HMG provides gonadotropin activity that supports reproductive function.
FSH stimulates the development of ovarian follicles in women. In men, FSH acts on Sertoli cells within the testes and supports sperm production. LH activity stimulates Leydig cells to produce testosterone, which contributes to normal testicular function and spermatogenesis.
The clinical response depends on the underlying condition, existing hormone levels, and individual physiology.
Clinical Applications
Female fertility
HMG is used in assisted reproductive treatments to stimulate the development of ovarian follicles under specialist supervision.
Male fertility
In selected cases of hypogonadotropic hypogonadism, HMG may be prescribed alongside human chorionic gonadotropin (HCG) to support sperm production. Treatment response can take several months and varies between individuals.
HMG and HCG
HMG and HCG have different roles in reproductive medicine.
HMG: Provides FSH and LH activity to support follicular development and reproductive function.
HCG: Activates LH receptors and can stimulate testosterone production in the testes or trigger final oocyte maturation in fertility treatment.
These medications are not interchangeable. Their use depends on the patient’s diagnosis and treatment objectives.
Shipping
We ship discreetly across Canada using tracked shipping.
- $25 standard shipping across Canada
- Free shipping on orders over $499
- Orders processed within 1–2 business days
- Tracking number provided via email
FAQ
Before reconstitution, this product is stable at room temperature for short periods, such as during shipping, but refrigeration is recommended for longer-term storage. After reconstitution, it must be refrigerated. Keep away from direct light. This product is stored refrigerated until it ships.
